VIAAT/SLC32A1/VGAT Antibody (731307) [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 731307
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

VIAAT/SLC32A1/VGAT Antibody (731307) [Janelia Fluor® 549] Summary

• Immunogen: E. coli-derived recombinant human VIAAT/SLC32A1
  Ala2-Phe133
  Accession # Q9H598
• Specificity: Detects human VIAAT/SLC32A1 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC32A1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for VIAAT/SLC32A1/VGAT Antibody (731307) [Janelia Fluor® 549]

• bA122O1.1
• hVIAAT
• SLC32A1
• solute carrier family 32 (GABA vesicular transporter), member 1
• Solute carrier family 32 member 1
• Vesicular GABA transporter
• vesicular inhibitory amino acid transporter
• VGAT
• VGATGABA and glycine transporter
• VIAAT

Background

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Acid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC32A1