VGLUT1 Antibody (732607) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: IHC
• Clone: 732607
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

VGLUT1 Antibody (732607) [Alexa Fluor® 594] Summary

• Immunogen: E.coli-derived recombinant human VGLUT/SLC17A7
  Asn93-Thr115
  Accession # Q9P2U7
• Specificity: Detects human VGLUT/SLC17A7 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VGLUT1 Antibody (732607) [Alexa Fluor® 594]

• BNPI
• BNPIbrain-specific Na-dependent inorganic phosphate cotransporter
• Brain-specific Na(+)-dependent inorganic phosphate cotransporter
• member 7
• SLC17A7
• solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)
• Solute carrier family 17 member 7
• VGLUT1
• VGLUT1vesicular glutamate transporter 1

Background

Vesicular glutamate transporter 1 (VGLUT1), also known as SLC17A7, is an integral membrane protein involved in glutamate uptake into synaptic vesicles. The vesicular glutamate transporter (VGLUT) mediates the accumulation of neurotransmitter (glutamate) into synaptic vesicles. It is expressed in pre-synaptic vesicles. VGLUT proteins appear to be differentially expressed in myelinated afferents located in specific axonal populations within the spinal cord. VGLUT proteins are among the most specific markers for the identification of glutamatergic neurons. It is an essential molecular component of glutamate synaptic transmission, and its de-regulation can result synaptic failure and excitotoxicity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.