VEGF-B Antibody [DyLight 350]

• Reactivity: Mu
• Applications: WB, B/N
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 350

VEGF-B Antibody [DyLight 350] Summary

• Immunogen: E. coli-derived recombinant mouse VEGF-B₁₈₆
  Pro22-Ala107
  Accession # P49766
• Specificity: Detects mouse VEGF-B₁₆₇ and mouse VEGF-B₁₈₆ in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with rhVEGF-B₁₈₆ is observed, 15% cross-reactivity with rhVEGF-B₁₆₇ is observed and less than 1% cross-reactivity with rmVEGF₁₆₄, rhVEGF-C and rmVEGF-D is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: Vegfa
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for VEGF-B Antibody [DyLight 350]

• vascular endothelial growth factor B
• VEGFB
• VEGF-B
• VEGF-related factor
• VRFVEGFL

Background

VEGFB 186 is an isoform of VEGFB (Vascular Endothelial Growth Factor B), a member of the vascular endothelial growth factor (VEGF) family. It is a growth factor for endothelial cells. Both isoforms of VEGFB show strong homology to VEGF at their amino termini, wheras the VEGFB167 isoform binds heparin, the C terminus of VEGFB-186 has no heparin binding domain, is less basic and more hydrophobic, and has no similarity to any published sequence. VEGFB 186 is secreted as a disulfide-linked homodimer and that, like VEGFB 167, this isoform can form disulfide-linked heterodimers with VEGF.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Vegfa