VEGF-B Antibody (RM0008-6E72)

Images

 
Immunohistochemistry-Paraffin: VEGFB Antibody (RM0008-6E72) [NB110-61024] - Paraffin lung section from LPS treated mice was subjected to IHC using anti VEGF-B antibody RM0008-6E72 (Righr Panel, Negative control).

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC, IHC-P
Clone
RM0008-6E72
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

VEGF-B Antibody (RM0008-6E72) Summary

Immunogen
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse VEGF-B (186).
Specificity
VEGFB (RM0008-6E72)
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
VEGFB
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:400-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody recognizes mouse VEGF-B 186 but not 167.

Reactivity Notes

This antibody is reactive against mouse. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for VEGF-B Antibody (RM0008-6E72)

  • vascular endothelial growth factor B
  • VEGFB
  • VEGF-B
  • VEGF-related factor
  • VRFVEGFL

Background

VEGFB 186 is an isoform of VEGFB (Vascular Endothelial Growth Factor B), a member of the vascular endothelial growth factor (VEGF) family. It is a growth factor for endothelial cells. Both isoforms of VEGFB show strong homology to VEGF at their amino termini, wheras the VEGFB167 isoform binds heparin, the C terminus of VEGFB-186 has no heparin binding domain, is less basic and more hydrophobic, and has no similarity to any published sequence. VEGFB 186 is secreted as a disulfide-linked homodimer and that, like VEGFB 167, this isoform can form disulfide-linked heterodimers with VEGF.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol VEGFB
Entrez