VEGF-B Antibody (RM0008-6E72) - Azide and BSA Free

Immunohistochemistry-Paraffin: VEGFB Antibody (RM0008-6E72) [NB110-61024] - Paraffin lung section from LPS treated mice was subjected to IHC using anti VEGF-B antibody RM0008-6E72 (Righr Panel, Negative control).

• Reactivity: Mu
• Applications: WB, IHC
• Clone: RM0008-6E72
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

VEGF-B Antibody (RM0008-6E72) - Azide and BSA Free Summary

• Immunogen: Mouse recombinant VEGF-B
• Specificity: This antibody recognizes mouse VEGF-B 186 but not 167
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: VEGFB
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:100
  • Western Blot 1:400-1:1000

Reactivity Notes

This antibody is reactive against mouse. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for VEGF-B Antibody (RM0008-6E72) - Azide and BSA Free

• vascular endothelial growth factor B
• VEGFB
• VEGF-B
• VEGF-related factor
• VRFVEGFL

Background

VEGFB 186 is an isoform of VEGFB (Vascular Endothelial Growth Factor B), a member of the vascular endothelial growth factor (VEGF) family. It is a growth factor for endothelial cells. Both isoforms of VEGFB show strong homology to VEGF at their amino termini, wheras the VEGFB167 isoform binds heparin, the C terminus of VEGFB-186 has no heparin binding domain, is less basic and more hydrophobic, and has no similarity to any published sequence. VEGFB 186 is secreted as a disulfide-linked homodimer and that, like VEGFB 167, this isoform can form disulfide-linked heterodimers with VEGF.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for VEGF-B Antibody (NB110-61024)(1)

Publication using NB110-61024

• Rothhammer V, Borucki DM, Tjon EC et al. Microglial control of astrocytes in response to microbial metabolites Nature 2018-05-01 [PMID: 29769726] (Mouse)

Bioinformatics

• Gene Symbol: VEGFB
• Entrez:
  • 22340(Mouse)