VDAC2 Antibody

Western Blot: VDAC2 Antibody [NB100-74560] - Analysis of VDAC2 expression from recombinant VDAC2 protein.

Product Discontinued

VDAC2 Antibody Summary

• Immunogen: VDAC2 Protein
• Specificity: This detects VDAC2 in mouse, rat, human, rabbit, and bovine samples.
• Isotype: IgY
• Clonality: Polyclonal
• Host: Chicken
• Gene: VDAC2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Western Blot 1:500
• Application Notes: WB: Detects approx. 30 kDa protein representing VDAC2.
• Control:

  VDAC2 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS with 1 mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for VDAC2 Antibody

• FLJ23841
• hVDAC2
• Outer mitochondrial membrane protein porin 2
• POR
• VDAC-2
• voltage-dependent anion channel 2
• voltage-dependent anion-selective channel protein 2

Background

VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. VDAC2 interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. It consists mainly of membrane spanning sided beta sheets, and belongs to the eukaryotic mitochondrial porin family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VDAC2
• Entrez:
  • 7417(Human)
  • 22334(Mouse)
  • 83531(Rat)