USP33 Antibody

Immunohistochemistry-Paraffin: USP33 Antibody [NB100-58767] - Analysis of anti-USP33 antibody with human kidney at concentration 5 ug/ml.

Product Discontinued

USP33 Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from internal region of human USP33.
• Epitope: internal domain of human protein
• Specificity: Human USP33. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Orangutan (100%), Monkey (94%), Primate (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USP33
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for USP33 Antibody

• Deubiquitinating enzyme 33
• EC 3.1.2.15
• EC 3.4.19.12
• hVDU1
• KIAA1097
• KIAA1097MGC16868
• pVHL-interacting deubiquitinating enzyme 1
• ubiquitin carboxyl-terminal hydrolase 33
• ubiquitin specific peptidase 33
• ubiquitin thioesterase 33
• Ubiquitin thiolesterase 33
• Ubiquitin-specific-processing protease 33
• USP33
• VDU1
• VDU1ubiquitin specific protease 33
• VHL-interacting deubiquitinating enzyme 1

Background

The ubiquitin dependent protein degradation pathway is essential for the proteolysis of intracellular proteins and peptides. Deubiquitination, is catalyzed by proteases called deubiquitinating enzymes. USP33 is a deubiquitinating enzyme that binds to the von Hippel-Lindau tumor suppressor protein. It also regulates thyroid hormone activation by deubiquitinating type 2 iodothyronine deiodinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: USP33
• Entrez:
  • 23032(Human)