USP33 Products

Description

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	23032
Alternate Names	Deubiquitinating enzyme 33 EC 3.1.2.15 EC 3.4.19.12 hVDU1 KIAA1097 KIAA1097MGC16868 pVHL-interacting deubiquitinating enzyme 1 ubiquitin carboxyl-terminal hydrolase 33 ubiquitin specific peptidase 33 ubiquitin thioesterase 33 Ubiquitin thiolesterase 33 Ubiquitin-specific-processing protease 33 USP33 VDU1 VDU1ubiquitin specific protease 33 VHL-interacting deubiquitinating enzyme 1

Research Areas for USP33

Find related products by research area and learn more about each of the different research areas below.

Protein Turnover
Ubiquitin Proteasome Pathway