URI Antibody

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Western Blot: URI Antibody [NB100-59777] - Detection of Human RMP on HeLa whole cell lysate using NB100-59777. RMP was also immunoprecipitated by rabbit anti-RMP antibody NB100-59778.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

URI Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 350 and 400 of human RNA polymerase II, subunit 5 (RPB5)-mediating protein using the numbering given in entry BAA34781.1 (GeneID 8725).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
URI1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 1:10-1:500
Positive Control
URI Lysate (NBL1-08262)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for URI Antibody

  • chromosome 19 open reading frame 2
  • FLJ10575
  • NNX3RPB5-mediating protein
  • Protein NNX3
  • RMPunconventional prefoldin RPB5 interactor
  • RNA polymerase II subunit 5-mediating protein
  • URIRNA polymerase II, subunit 5-mediating protein

Background

The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol URI1
Entrez
Uniprot