URI Products

Description

The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Bioinformatics

Entrez	8725 Human
Product By Gene ID	8725
Alternate Names	chromosome 19 open reading frame 2 FLJ10575 NNX3RPB5-mediating protein Protein NNX3 RMPunconventional prefoldin RPB5 interactor RNA polymerase II subunit 5-mediating protein URIRNA polymerase II, subunit 5-mediating protein