UNC13D/Munc 13-4 Antibody (1222B) [DyLight 755]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clone: 1222B
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: DyLight 755

UNC13D/Munc 13-4 Antibody (1222B) [DyLight 755] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: KLH-coupled N-terminal human UNC13D peptide of an alternative isoform described in PMID:24842371
  Accession # EAW89322
• Specificity: Detects the alternate form of human UNC13D in Western blots.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: UNC13D
• Purity: Protein A or G purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from cell culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for UNC13D/Munc 13-4 Antibody (1222B) [DyLight 755]

• FHL3
• HLH3
• HPLH3
• Munc13-4
• Munc13-4protein unc-13 homolog D
• unc-13 homolog D (C. elegans)
• UNC13D

Background

Munc 13-4 encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for UNC13D/Munc 13-4 Antibody (FAB8966Z). (Showing 1 - 1 of 1 FAQ).

1. I'm looking Munc13-4 N terminal antibody with related epitope sequence.
   • Unfortunately we do not epitope map our antibodies, but we do have a whole list of antibodies against your target depending on species reactivity and application you want to use them for. Please see this link to our MUNC 13-4 antibodies. All of the immunogen information that is not proprietary, or known should be presented on the datasheet. Often times a range will be provided where the peptide falls within, or if it was raised against a larger recombinant protein as is the case for the one you inquired about we do not know exactly where the binding occurs.

Bioinformatics

• Gene Symbol: UNC13D