STX11 Antibody - BSA Free

Immunohistochemistry-Paraffin: STX11 Antibody [NBP1-86122] - Staining of human lymph node shows strong cytoplasmic positivity in reaction center cells.

Western Blot: STX11 Antibody [NBP1-86122] - Analysis in control (vector only transfected HEK293T lysate) and STX11 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Analysis in human cell line HDLM-2.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

STX11 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: DIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STX11
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: WB reported in scientific literature (PMID: 26176172). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  STX11 Protein (NBP1-86122PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (84%). Human reactivity reported in scientific literature (PMID: 26176172).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for STX11 Antibody - BSA Free

• FHL4
• HLH4
• HPLH4
• syntaxin 11
• syntaxin-11

Background

STX11 encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for STX11 Antibody (NBP1-86122)(1)

Publication using NBP1-86122

• Yoshida N, Tsuzuki S, Karube K et al. STX11 functions as a novel tumor suppressor gene in peripheral T-cell lymphomas. Cancer Sci 2015-10-01 [PMID: 26176172] (WB, Human)

Bioinformatics

• Gene Symbol: STX11