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HAF008). A specific band was detected for UNC13D at approximately 110 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF008). A specific band was detected for UNC13D at approximately 110 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
Munc 13-4 encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
![Western Blot UNC13D/Munc 13-4 Antibody (1223A) [Unconjugated]](http://images.novusbio.com/images/antibody/UNC13D_MAB89661_Western_Blot_19237.jpg)
![Western Blot UNC13D/Munc 13-4 Antibody (1222B) [Unconjugated]](http://images.novusbio.com/images/antibody/UNC13D_MAB8966_Western_Blot_19234.jpg)
![Immunocytochemistry UNC13D/Munc 13-4 Antibody (1223A) [Unconjugated]](http://images.novusbio.com/images/antibody/UNC13D_MAB89661_Immunocytochemistry__Immunofluorescence_18947.jpg)
![Simple Western UNC13D/Munc 13-4 Antibody (1223A) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/UNC13D_MAB89661_Simple_Western_19258.jpg)
![Immunocytochemistry UNC13D/Munc 13-4 Antibody (1222B) [Unconjugated]](http://images.novusbio.com/images/antibody/UNC13D_MAB8966_Immunocytochemistry__Immunofluorescence_18946.jpg)
![Simple Western UNC13D/Munc 13-4 Antibody (1222B) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/UNC13D_MAB8966_Simple_Western_19257.jpg)
