WB, ICC/IF, IHC, IHC-P, PEP-ELISAHost:
WB, Simple Western, ICC/IFHost:
Applications: WB, Simple Western, ICC/IF
Host: Rabbit Monoclonal
Applications: WB, ELISA, PA, AP
Munc 13-4 encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Bioinformatics Tool for UNC13D/Munc 13-4
Discover related pathways, diseases and genes to UNC13D/Munc 13-4. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.