ULBP-3 Antibody (MM0594-6E12) - Azide and BSA Free

Immunohistochemistry-Paraffin: ULBP-3 Antibody (MM0594-6E12) [NBP2-11988] - 4% PFA fixed and parffine embedded human placental tissue section (4um) is subjected to IHC staining. Tissue was treated with 15ug/ml Protenase for antige retrieval before IHC is applied.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: MM0594-6E12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

ULBP-3 Antibody (MM0594-6E12) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse ULBP-3 Antibody (MM0594-6E12) - Azide and BSA Free (NBP2-11988) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant ULBP-3
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: ULBP3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 15 ug/ml
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for ULBP-3 Antibody (MM0594-6E12) - Azide and BSA Free

• NKG2D ligand 3
• RAET1N
• UL16 binding protein 3
• ULBP3
• ULBP-3

Background

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than doesULBP2 or ULBP1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ULBP3
• Uniprot:
  • NP_078794()