Species: Hu
Applications: Flow, B/N, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB, B/N
Host: Goat Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: Binding Activity
Applications: Bioactivity
Species: Hu
Applications: AC
Description
Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than doesULBP2 or ULBP1
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
79465 |
| Alternate Names |
- NKG2D ligand 3
- RAET1N
- UL16 binding protein 3
|
![Flow Cytometry ULBP-3 Antibody (166510) [Unconjugated]](http://images.novusbio.com/fullsize/mab1517_human-ulbp-3-mab-clone-166510-41202410482416.jpg)
![N/A ULBP-3 [Biotin]](http://images.novusbio.com/fullsize2/DATA_ULBP3_DY151705_ELISA_2362.jpg)
![Binding Activity ULBP-3 [Unconjugated]](http://images.novusbio.com/fullsize/11255-ul_recombinant-human-ulbp-3-his-tag-protein-cf-binding-activity-152202395425.jpg)
![SDS-PAGE ULBP-3 [Unconjugated]](http://images.novusbio.com/fullsize/11255-ul_recombinant-human-ulbp-3-his-tag-protein-cf-sds-page-2092022104248.jpg)