UCP3 Antibody

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Western Blot: UCP3 Antibody [NB100-2041] - Detection of recombinant human UCP-3.

Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

UCP3 Antibody Summary

Immunogen
Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.
Localization
Mitochondrial
Specificity
Detects UCP 3 from human, rat and mouse tissues. This does not detect UCP 3 from mouse liver or kidney.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
UCP3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5-2 ug/ml
Application Notes
WB: Detects an approx. 30 kDa protein representing UCP 3 from rat heart homogenate.
Publications
Read Publications using NB100-2041.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1 mg/ml BSA
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for UCP3 Antibody

  • mitochondrial uncoupling protein 3
  • SLC25A9Solute carrier family 25 member 9
  • UCP 3
  • uncoupling protein 3 (mitochondrial, proton carrier)
  • Uncoupling protein-3

Background

The uncoupling proteins (UCPs) are found in the inner mitochondrial membranes and belong to a family of mitochondrial anion transport proteins that include the phosphate and oxologutarate carriers and the ADP/ATP translocator. Three UCP subtypes have been identified and cloned. UCP 1 is abundantly expressed in brown adipose tissue of mammals. UCP 1 allows proton re-entry into the mitochondrial matrix without involving the F0-F1 ATPase which produces heat instead of ATP. It is thought that UCP 2 and 3 also dissipate the mitochondrial proton gradient produced by the respiratory chain in cells and tissues within which they are expressed. Studies have shown UCP 2 to be expressed by a variety of tissues. UCP 3 is expressed predominantly in brown adipose tissue, skeletal muscle, at lower levels in heart and smooth muscle, and is absent in liver and kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for UCP3 Antibody (NB100-2041)(2)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol UCP3
Entrez
Uniprot