TXNL1 Antibody (1A10) - Azide and BSA Free

Western Blot: TXNL1 Antibody (1A10) [H00009352-M01] - TXNL1 monoclonal antibody (M01), clone 1A10 Analysis of TXNL1 expression in HL-60.

Sandwich ELISA: TXNL1 Antibody (1A10) [H00009352-M01] - Detection limit for recombinant GST tagged TXNL1 is approximately 1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: 1A10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

TXNL1 Antibody (1A10) - Azide and BSA Free Summary

• Immunogen: TXNL1 (AAH01156, 190 a.a. ~ 289 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH
• Localization: Cytoplasmic
• Specificity: TXNL1 - thioredoxin-like 1
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TXNL1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TXNL1 Antibody (1A10) - Azide and BSA Free

• 32 kDa thioredoxin-related protein
• thioredoxin-like 1
• thioredoxin-like, 32kDa
• thioredoxin-related 32 kDa protein
• thioredoxin-related protein 1
• TRP32thioredoxin-like protein 1
• Txl
• TXL-1
• TXNL

Background

Thioredoxins are a group of small redox active proteins which have a conserved active site sequence. The predicted 32.3-kD protein of TXNL1 (Thioredoxin like protein 1) has 2 distinct domains: an N terminal domain, which is 43% identical to human TXN, and a C terminal domain, which showed no homology to other proteins in the sequence databases. The active site sequence, located within the N terminal domain, is that of a thioredoxin like protein; compared to the active site sequence of TXN, it has a single amino acid substitution. Unlike other thioredoxin like proteins, TXNL1 did not act as a substrate for thioredoxin reductase in an insulin assay.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TXNL1 Antibody (H00009352-M01)(1)

Publication using H00009352-M01

• Gemoll T, Roblick UJ, Szymczak S et al. HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers. Cell Mol Life Sci 2011-02-03 [PMID: 21290163]

Bioinformatics

• Gene Symbol: TXNL1
• Entrez:
  • 9352(Human)
• OMIM:
  • 603049(Human)
• Uniprot:
  • AAH01156(Human)