Western Blot: TXNIP Antibody (JY2) [NBP1-54578] - Western blot analysis of TXNIP expression in Raji (1), K562 (2), KG1 (3), MRC5 (4), IC2Tr (5), HEL (6), P19 (7) and WR19L (8).
Immunohistochemistry-Paraffin: TXNIP Antibody (JY2) [NBP1-54578] - IHC analysis of a formalin fixed and paraffin embedded tissue section of mouse kidney using TXNIP antibody (clone JY2) at 1:100 dilution. The signal was ...read more
Immunohistochemistry-Paraffin: TXNIP Antibody (JY2) [NBP1-54578] - IHC analysis of a formalin fixed and paraffin embedded tissue section of mouse kidney using TXNIP antibody (clone JY2) at 1:250 dilution. The signal was ...read more
Immunoprecipitation: TXNIP Antibody (JY2) [NBP1-54578] - Immunoprecipitation of Txnip/VDUP1 from Raji with NBP1-54578 (1) or mouse IgG1 (2).
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
Protein A or G purified
Alternate Names for TXNIP Antibody (JY2)
thioredoxin binding protein 2
thioredoxin interacting protein
Thioredoxin-binding protein 2
upregulated by 1,25-dihydroxyvitamin D-3
Vitamin D3 up-regulated protein 1
Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that TXNIP plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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