TULA/STS-2 Antibody [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 549

TULA/STS-2 Antibody [Janelia Fluor® 549] Summary

• Immunogen: Produced in rabbits immunized with purified, recombinant Human TULA/STS-2 (Accession#: AAH69511.1; Ala354-Asn623)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: UBASH3A
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TULA/STS-2 Antibody [Janelia Fluor® 549]

• Cbl-interacting protein 4
• gene similar to UBA containing SH3 domain10CLIP4STS-2T-cell ubiquitin ligand protein
• STS2
• Suppressor of T-cell receptor signaling 2
• T-cell ubiquitin ligand
• TULAubiquitin-associated and SH3 domain-containing protein A
• ubiquitin associated and SH3 domain containing A

Background

UBASH3A, ubiquitin associated and SH3 domain containing, A, interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface (referenced from Swiss Prot).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UBASH3A