TRP2 Antibody

Product Discontinued

TRP2 Antibody Summary

• Immunogen: The antiserum was produced against synthesized peptide derived from human DCT. The immunogen region is: Internal.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DCT
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:4000
  • Immunocytochemistry/ Immunofluorescence 1:100-1:500
  • Western Blot 1:500-1:1000
• Theoretical MW: 59 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TRP2 Antibody

• dopachrome delta-isomerase
• dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)
• DT
• EC 5.3.3.12
• L-dopachrome tautomerase
• TRP2
• TRP-2
• Tyrosinase-related protein 2
• TYRP2
• TYRP2L-dopachrome Delta-isomerase

Background

TRP2 is involved in regulating eumelanin and phaeomelanin levels

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TRP2 Antibody (NBP1-56058)(1)

Publication using NBP1-56058

• Yang CH, Huang YC, Tsai ML et al. Inhibition of Melanogenesis by Beta-Caryophyllene from Lime Mint Essential Oil in Mouse B16 Melanoma Cells. Int J Cosmet Sci. 2015-03-26 [PMID: 25819153] (WB, Mouse)

FAQs for TRP2 Antibody (NBP1-56058). (Showing 1 - 1 of 1 FAQ).

1. Do you have additional info concerning the part of the peptide(Trp2) the antibody was made against? I am looking for an antibody specific against TRP-2 (aa180-188).
   • The amino acid range that this antibody detects is aa50-100 of human L-dopachrome tautomerase with accession number P40126 (https://www.uniprot.org/uniprotkb/P40126/entry). This antibody binds to the lumenal topological domain (based upon prediction).

Bioinformatics

• Gene Symbol: DCT
• Entrez:
  • 1638(Human)
  • 13190(Mouse)
• Uniprot:
  • P40126(Human)