TROY/TNFRSF19 Antibody [Janelia Fluor® 549]

• Reactivity: Mu
• Applications: WB, IHC, ELISA, ELISA(Cap), ELISA(Det)
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 549

TROY/TNFRSF19 Antibody [Janelia Fluor® 549] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TROY/TNFRSF19
  Glu30-Leu170
  Accession # Q9JLL3
• Specificity: Detects mouse TROY/TNFRSF19 in ELISAs and Western blots. In sandwich immunoassays, less than 2% cross-reactivity with recombinant human TAJ is observed and less than 0.2% cross-reactivity with recombinant mouse (rm) EDAR, rmCD27, rmFas, rmRANK, rmTNF RI, and rmTNF RII is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TNFRSF19
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TROY/TNFRSF19 Antibody [Janelia Fluor® 549]

• TAJ
• TAJ-alpha
• TAJToxicity and JNK inducer
• TNFRSF19
• TRADE
• TROY
• TROYtumor necrosis factor receptor superfamily member 19
• tumor necrosis factor receptor superfamily, member 19

Background

TROY is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate the JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNFRSF19