Troponin T Type 2 (cardiac) Antibody (1C11)

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Sandwich ELISA: Troponin T Type 2 (cardiac) Antibody (1C11) [NB200-412] - Calibrating curves for sandwich cTnT fluoroimmunoassay with different animal TnTs as antigen: human, canine, rat, mouse Clone 1C11 for capture ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications IA, S-ELISA
Clone
1C11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Troponin T Type 2 (cardiac) Antibody (1C11) Summary

Immunogen
Full length purified native protein (Human).
Localization
Located on the thin filament of striated muscles.
Specificity
This is specific for cadiac troponin. Does not cross-react with skeletal muscle troponin T, cTnI and TnC.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNNT2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoassay
  • Sandwich ELISA 1:100-1:2000
Application Notes
This antibody is useful for Troponin T immunoassay. It is possible to use following pairs of antibodies for sandwich immunoassay (coating - conjugate): NB200-412(Coating)-NBP1-79059(Conjugate)NB200-412(Coating)-NB120-10222(Conjugate)NB120-10223(Coating)-NB200-412(Conjugate)NB200-412(Coating)-NBP1-79060(Conjugate)This antibody will work best as a capture for BIAcore
Control
Troponin T Type 2 (cardiac) Lysate (NBL1-17180)

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Troponin T Type 2 (cardiac) Antibody (1C11)

  • cardiac
  • CMD1D
  • CMPD2
  • dilated 1D (autosomal dominant)
  • hypertrophic 2
  • MGC3889
  • RCM3
  • TnTc
  • troponin T type 2 (cardiac)
  • troponin T, cardiac muscle

Background

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue-specific isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Troponin T Type 2 (cardiac) Antibody (NB200-412). (Showing 1 - 1 of 1 FAQ).

  1. What is the concentration of NB200-412 LOT 17/09-T19-C11?
    • The concentration of the lot 17/09-T19-C11 at 8.0 mg/ml.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TNNT2
Entrez