tropomyosin-3 Antibody

Product Discontinued

tropomyosin-3 Antibody Summary

• Immunogen: This antibody was made against a protein fragment from the Middle Region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TPM3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Western Blot 1:5000 - 1:20000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Potassium Phosphate (pH 7.0), 0.15 M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs. These products are available in limited quantities. Please enquire about the availability of this product before purchasing.

Alternate Names for tropomyosin-3 Antibody

• cytoskeletal tropomyosin TM30
• FLJ41118
• gamma-tropomyosin
• heat-stable cytoskeletal protein 30 kDa
• hscp30
• hTM5
• MGC14582
• MGC3261
• MGC72094
• NEM1
• OK/SW-cl.5
• TM3
• TM30
• TM30nm
• TM-5
• TPMsk3
• TRK
• tropomyosin 3
• tropomyosin alpha-3 chain
• tropomyosin gamma
• tropomyosin-3
• tropomyosin-5

Background

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for tropomyosin-3 Antibody (22720002)(2)

Publications using 22720002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Review for tropomyosin-3 Antibody (22720002) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer ELISA Human 11/09/2018

Summary

• Application: ELISA
• Sample Tested: Serum and Plasma
• Species: Human
• Lot: T01301A01

Bioinformatics

• Gene Symbol: TPM3
• Entrez:
  • 7170(Human)
• Uniprot:
  • P06753(Human)