FAQs for TREX1 Antibody (NBP1-89202). (Showing 1 - 1 of 1 FAQ).
Is there any possibility that Trex1 expression is detected in cells from WT mouse on immunocytochemistry staining?
Unfortunately, we have not yet validated this antibody in mouse, so I do not have much information as to how it may or may not detect the mouse protein vs. the human protein. The sequence used to generate this antibody is 80% homologous to the mouse sequence, so there is definitely a chance of detection possible.
Dinosaur Protein Names: Infographic Trex1 the protein is involved in DNA damage response. Tyrannosaurus rex (T. rex) the dinosaur lived during the Cretaceous Period. Raptor the protein is a regulator of mTOR activity. Velociraptors the dinosaurs lived during the Cretaceous Period. Learn... Read full blog post.
Trex1 (3'-5' exonuclease TREX1, DNase III) This gene encodes the major 3' to 5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that appears to provide proofreading for checkpoint signaling after DNA damage in response to oxidative stress and apoptosis. It is ubiqui... Read full blog post.
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