Transferrin Antibody - BSA Free

• Reactivity: Mu
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Transferrin Antibody - BSA Free Summary

• Description: Novus Biologicals Goat Transferrin Antibody - BSA Free (NB110-82403) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. Anti-Transferrin Antibody: Cited in 3 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Transferrin
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TF
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:1000 - 1:30000
  • Immunocytochemistry/ Immunofluorescence 1:200-1:2000
  • Immunohistochemistry 1:200-1:2000
  • Immunohistochemistry-Paraffin 1:200-1:2000
  • Western Blot 1:1000 - 1:30000
• Application Notes: ELISA 1:1,000 - 1:30,000; for coating plates 1:100 - 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Transferrin Antibody - BSA Free

• Beta-1 metal-binding globulin
• DKFZp781D0156
• EC 3.4.21
• PRO1557
• PRO2086
• Serotransferrin
• Siderophilin
• TF
• Transferrin

Background

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, eticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as ranulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Transferrin Antibody (NB110-82403)(3)

Publications using NB110-82403

• DeGregorio-Rocasolano N, Marti-Sistac O, Ponce J et al. Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage. Redox Biol 2017-12-02 [PMID: 29248829] (IF/IHC, Mouse)
• Luijten M, Zwart EP, Dolle ME et al. Evaluation of the LacZ reporter assay in cryopreserved primary hepatocytes for In vitro genotoxicity testing. Environ. Mol. Mutagen. 2016-12-01 [PMID: 27859631] (Mouse)
• Dougan SK, Hu CC, Paquet ME et al. Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes Mol Cell Biol 2011-03-01 [PMID: 21220515] (WB, Mouse)

Bioinformatics

• Gene Symbol: TF
• Entrez:
  • 22041(Mouse)