TNF RII/TNFRSF1B Antibody Pair [HRP] Summary
| Description |
Solid Phase sandwich ELISA for the quantitative determination of Mouse TNF RII/TNFRSF1B. |
| Additional Information |
Recombinant Monoclonal Antibody |
| Specificity |
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Mouse TNF RII/TNFRSF1B. |
| Source |
HEK293 |
| Standard Curve Range |
9.38-600 pg/ml (example only; lot dependent) |
| Sensitivity |
9.4 pg/ml (example only; lot dependent) |
| Assay Type |
Sandwich ELISA |
| Sample Volume |
100 ul |
| Gene |
TNFRSF1B |
Applications/Dilutions
Packaging, Storage & Formulations
| Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Alternate Names for TNF RII/TNFRSF1B Antibody Pair [HRP]
Background
Tumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNF Receptor I and TNF Receptor II) that are included in the TNF receptor superfamily along with FAS antigen and CD40. TNF receptors I and II are 55 and 75 kDa members, respectively, of a family of cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, OX40, and 4-1BB, which are characterized by cysteine rich motifs in the extracellular domain. TNF Receptor II (p75, CD120b) is present on most cell types (including monocytes, endothelial cells, Langerhans cells, and macrophages) and is considered to play a role in cell stimulation by TNF alpha. TNF Receptor II molecule is shown to be responsible for stimulation of activated T lymphocytes by TNF alpha.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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