TIP30 Antibody

Western Blot: TIP30 Antibody [NB100-1415] - (0.6ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

TIP30 Antibody Summary

• Description: Novus Biologicals Goat TIP30 Antibody (NB100-1415) is a polyclonal antibody validated for use in WB and ELISA. Anti-TIP30 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence AETEALSKLREDFR-C corresponding to N-Terminus according to NP_001091990.1, NP_006401.3, NP_001091991.1, NP_001091992.1, NP_001091993.1.
• Specificity: This antibody is expected to recognise all three reported isoforms. Variants (NP_006401.3; NP_001091991.1; NP_001091992.1) encode the same isoform.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: HTATIP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.3 - 1 ug/ml
• Application Notes: WB: Approx. 28 kDa band observed in HeLa lysates (calculated MW of 27.0 kDa band according to NP_006401.3).
• Control:

  HeLa Whole Cell Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TIP30 Antibody

• 30 kDa HIV-1 TAT-interacting protein
• CC3oxidoreductase HTATIP2
• EC 1.1.1
• EC 1.1.1.-
• FLJ26963
• HIV-1 Tat interactive protein 2, 30 kDa
• HIV-1 Tat interactive protein 2, 30kDa
• HIV-1 TAT-interactive protein 2
• SDR44U1
• Tat-interacting protein (30kD)
• TIP30short chain dehydrogenase/reductase family 44U, member 1

Background

TIP30, also called CC3 or HTATIP2, is a putative metastasis suppressor that promotes apoptosis and inhibits angiogenesis. Although TIP30 has several characteristic features of a tumor suppressor in in vitro analyses, tumor development as a result of TIP30 inactivation has not been demonstrated in vivo, and abnormal expression of TIP30 in human cancer has not been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TIP30 Antibody (NB100-1415)(1)

Publication using NB100-1415

• Shtivelman E. A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma. Oncogene 1997-05-08 [PMID: 9174052]

Bioinformatics

• Gene Symbol: HTATIP2
• Entrez:
  • 10553(Human)
• Uniprot:
  • NP_006401.(Human)