TIMP-3 Antibody (183551) [FITC]

• Reactivity: Hu
• Applications: WB, IHC, IP, ELISA, ELISA(Cap), ELISA(Det)
• Clone: 183551
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

TIMP-3 Antibody (183551) [FITC] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human TIMP-3
  Cys24-Pro211
  Accession # P35625
• Specificity: Detects human TIMP-3 in ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human TIMP-1, -2, or -4 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TIMP3
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for TIMP-3 Antibody (183551) [FITC]

• HSMRK222
• K222
• K222TA2
• metalloproteinase inhibitor 3
• MIG-5 protein
• Protein MIG-5
• pseudoinflammatory)
• SFD
• TIMP metallopeptidase inhibitor 3
• TIMP3
• TIMP-3
• tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy
• Tissue inhibitor of metalloproteinases 3

Background

TIMPs form tight inhibitory complexes with MMPs, which are involved in matrix degradation and in tumor invasiveness and metastasis. TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TIMP3