TIM-2 Antibody (RM0134-5B23) [DyLight 550]

• Reactivity: Mu
• Applications: WB, IHC
• Clone: RM0134-5B23
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 550

TIM-2 Antibody (RM0134-5B23) [DyLight 550] Summary

• Description: This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
• Immunogen: Mouse recombinant protein of TIM-2
• Specificity: This antibody does not cross-react with mouse TIM-1 and TIM-3.
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TIM-2 Antibody (RM0134-5B23) [DyLight 550]

• G9D3
• T-cell immunoglobulin and mucin domain-containing protein 2
• T-cell immunoglobulin mucin receptor 2
• T-cell membrane protein 2
• TIM2
• TIM-2
• TIMD-2

Background

Tim-2 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-2. It is expressed on activated T cells and preferentially on differentiated Th2 cells. Sema4A is the ligand of Tim-2. A blockade of Tim-2/Tim-2 ligand interaction results in T cell hyperproliferation and Th2 cytokine production. Tim-2 plays a critical role in the development of atopic disease and other Th2-biased immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.