Thymidylate Synthase Antibody (TS106 + TMS715) [Biotin]

Images

 
There are currently no images for Thymidylate Synthase Antibody (NBP2-34503B).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC-Fr, IHC-P
Clone
TS106 + TMS715
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Thymidylate Synthase Antibody (TS106 TMS715) [Biotin] Summary

Immunogen
Recombinant human thymidylate synthase
Localization
Nuclear & Cytoplasmic
Marker
5-FU Resistance Marker
Specificity
It recognizes a protein of 36kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
TYMS
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Thymidylate Synthase Antibody (TS106 TMS715) [Biotin]

  • EC 2.1.1.45
  • HsT422
  • MGC88736
  • thymidylate synthase
  • thymidylate synthetase
  • TMSTsase
  • TSase
  • TSHST422

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

H00001806-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
H00001719-M01
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
NBP2-45397
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-01693
Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
MAB9521
Species: Hu, Mu
Applications: WB, IHC, IP
NBP2-37607
Species: Hu, Rt
Applications: WB, ELISA, IHC
NBP1-85896
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB200-103
Species: Hu, Mu, Rt, Ye, Xp(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready
NBP1-28872
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP1-87822
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-87466
Species: Hu, Rt
Applications: ICC/IF, IHC, IHC-P
AF1095
Species: Hu
Applications: WB, Simple Western, IHC, CyTOF-ready, ICC, ICFlow
NBP2-48965
Species: Hu
Applications: IHC
NBP1-59904
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-87441
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB500-418
Species: Hu, Po, Rb
Applications: WB, B/N, ELISA, ICC/IF, IHC, IHC-P, RIA
NBP2-29463
Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
NBP1-26612
Species: Hu
Applications: IP (-), WB
NBP1-87741
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-34503B
Species: Hu
Applications: WB, ICC/IF, IHC-Fr, IHC-P

Publications for Thymidylate Synthase Antibody (NBP2-34503B) (0)

There are no publications for Thymidylate Synthase Antibody (NBP2-34503B).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Thymidylate Synthase Antibody (NBP2-34503B) (0)

There are no reviews for Thymidylate Synthase Antibody (NBP2-34503B). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Thymidylate Synthase Antibody (NBP2-34503B) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Thymidylate Synthase Products

Related Products by Gene

Bioinformatics Tool for Thymidylate Synthase Antibody (NBP2-34503B)

Discover related pathways, diseases and genes to Thymidylate Synthase Antibody (NBP2-34503B). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Thymidylate Synthase Antibody (NBP2-34503B)

Discover more about diseases related to Thymidylate Synthase Antibody (NBP2-34503B).
 

Pathways for Thymidylate Synthase Antibody (NBP2-34503B)

View related products by pathway.

PTMs for Thymidylate Synthase Antibody (NBP2-34503B)

Learn more about PTMs related to Thymidylate Synthase Antibody (NBP2-34503B).
 

Research Areas for Thymidylate Synthase Antibody (NBP2-34503B)

Find related products by research area.

Blogs on Thymidylate Synthase

There are no specific blogs for Thymidylate Synthase, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Thymidylate Synthase Antibody (TS106 TMS715) [Biotin] and receive a gift card or discount.

Bioinformatics

Gene Symbol TYMS

Customers Who Bought This Also Bought