Thymidylate Synthase Products

Antibodies
Thymidylate Synthase Antibody ...
Thymidylate Synthase Antibody
NBP1-36638
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Thymidylate Synthase Antibody ...
Thymidylate Synthase Antibody Pair
H00007298-AP21
Species: Hu
Applications: S-ELISA
Lysates
Thymidylate Synthase Overexpr ...
Thymidylate Synthase Overexpressio...
H00007298-T01
Species: Hu
Applications: WB
Thymidylate Synthase Overexpr ...
Thymidylate Synthase Overexpressio...
NBP2-08333
Applications: WB
Proteins
Thymidylate Synthase Recombin ...
Thymidylate Synthase Recombinant P...
H00007298-P01
Species: Hu
Applications: WB, ELISA, PA
Thymidylate Synthase Partial ...
Thymidylate Synthase Partial Recom...
H00007298-Q01
Species: Hu
Applications: WB, ELISA, PA
Thymidylate Synthase Recombin ...
Thymidylate Synthase Recombinant P...
NBP1-30310
Species: Hu
Applications: PAGE
RNAi
Thymidylate Synthase RNAi
Thymidylate Synthase RNAi
H00007298-R01
Species: Hu

Description

Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 7298
Alternate Names
  • thymidylate synthase
  • EC 2.1.1.45
  • MGC88736
  • TSase
  • TSHST422
  • TMSTsase
  • HsT422
  • thymidylate synthetase

Research Areas for Thymidylate Synthase

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
DNA Repair
DNA replication, Transcription, Translation and Splicing

PTMs for Thymidylate Synthase

Learn more about PTMs related to Thymidylate Synthase.

Methylation
Phosphorylation
Dephosphorylation
Reduction
Acetylation
Demethylation
Sumoylation
Biotinylation

Bioinformatics Tool for Thymidylate Synthase

Discover related pathways, diseases and genes to Thymidylate Synthase. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.