Thrombomodulin/BDCA-3 Antibody (6C8.2F9) [Allophycocyanin]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow
Clone
6C8.2F9
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Thrombomodulin/BDCA-3 Antibody (6C8.2F9) [Allophycocyanin] Summary

Immunogen
Partial recombinant human CD141 protein (between amino acids 200-400) [UniProt P07204].
Localization
Transmembrane protein with Extracellular, Helical and Cytoplasmic domains.
Marker
Endothelial Cells Damage Marker
Isotype
IgG1 Lambda
Clonality
Monoclonal
Host
Mouse
Gene
THBD
Purity
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Thrombomodulin is a 575 amino acids long protein with predicted molecular weight of 60.3 kDa, however, the post translationally modified /glycosylated protein may run at relatively higher molecular weight position on Western blot. Endothelial cells are unique in synthesizing thrombomodulin protein, but its presence in some other cell types such as dendritic cells/PBMCs has also been reported.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
60.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Thrombomodulin/BDCA-3 Antibody (6C8.2F9) [Allophycocyanin]

  • BDCA3
  • BDCA-3
  • CD141 antigen
  • CD141
  • Fetomodulin
  • THBD
  • THRM
  • Thrombomodulin
  • TM

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP2-42213AF405
Alexa Fluor 488 Labeled NBP2-42213AF488
Alexa Fluor 647 Labeled NBP2-42213AF647
Alexa Fluor 700 Labeled NBP2-42213AF700
Biotin Labeled NBP2-42213B
DyLight 350 Labeled NBP2-42213UV
DyLight 405 Labeled NBP2-42213V
DyLight 488 Labeled NBP2-42213G
DyLight 550 Labeled NBP2-42213R
DyLight 650 Labeled NBP2-42213C
DyLight 680 Labeled NBP2-42213FR
DyLight 755 Labeled NBP2-42213IR
HRP Labeled NBP2-42213H
PE Labeled NBP2-42213PE
PerCP Labeled NBP2-42213PCP

Additional Array Products

Bioinformatics Tool for Thrombomodulin/BDCA-3 Antibody (NBP2-42213APC)

Discover related pathways, diseases and genes to Thrombomodulin/BDCA-3 Antibody (NBP2-42213APC). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Thrombomodulin/BDCA-3 Antibody (NBP2-42213APC)

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Pathways for Thrombomodulin/BDCA-3 Antibody (NBP2-42213APC)

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PTMs for Thrombomodulin/BDCA-3 Antibody (NBP2-42213APC)

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Blogs on Thrombomodulin/BDCA-3.

Thrombomodulin - A multifunctional protein with roles in inflammation and coagulation
Thrombomodulin, also known as BDCA-3, is a glycosylated transmembrane protein present on the surface of vascular endothelial cells. Thrombomodulin is a high-affinity receptor for thrombin, a key protein in the coagulation cascade. Formation of the...  Read full blog post.

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Bioinformatics

Gene Symbol THBD