WB, Flow, IHC, IHC-PHost:
WB, Flow, IP, CyTOF-ready, ICC/IFHost:
WB, Flow, IHC, CyTOF-ready, ICC/IFHost:
CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.
|Product By Gene ID
- CD141 antigen