Thrombomodulin/BDCA-3 Products

Antibodies
Thrombomodulin/BDCA-3 Antibod ...
Thrombomodulin/BDCA-3 Antibody [Un...
AF3894
Species: Mu
Applications: WB, Flow, IP, CyTOF-ready, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Proteins
Thrombomodulin/BDCA-3 Recombi ...
Thrombomodulin/BDCA-3 Recombinant ...
NBP1-88133PEP
Species: Hu
Applications: AC
Recombinant Human Thrombomodu ...
Recombinant Human Thrombomodulin/B...
H00007056-G01
Species: Hu
RNAi
Thrombomodulin/BDCA-3 RNAi
Thrombomodulin/BDCA-3 RNAi
H00007056-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 7056
Alternate Names
  • fetomodulin
  • TM
  • CD141 antigen
  • BDCA3
  • CD141
  • thrombomodulin

PTMs for Thrombomodulin/BDCA-3

Learn more about PTMs related to Thrombomodulin/BDCA-3.

Methylation
Demethylation
Cleavage
Phosphorylation
Deacetylation

Bioinformatics Tool for Thrombomodulin/BDCA-3

Discover related pathways, diseases and genes to Thrombomodulin/BDCA-3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related Thrombomodulin/BDCA-3 Blog Posts

Check out the latest blog posts on Thrombomodulin/BDCA-3.
Thrombomodulin - A multifunctional protein with roles in inflammation and coagulation
Thrombomodulin, also known as BDCA-3, is a glycosylated transmembrane protein present on the surface of vascular endothelial cells. Thrombomodulin is a high-affinity receptor for thrombin, a key protein in the coagulation cascade. Formation of the...    Read more.
Read more Thrombomodulin/BDCA-3 related blogs.