Thioredoxin Reductase 1/TRXR1 Antibody

Images

 
Western Blot: thioredoxin reductase 1 Antibody [NBP2-20619] - 50 ug Rat brain lysate/extract 7. 5% SDS-PAGE TrxR1 antibody [N3C2], Internal dilution: 1:1000.
Immunocytochemistry/ Immunofluorescence: thioredoxin reductase 1 Antibody [NBP2-20619] - Analysis of paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-20619] - TrxR1 antibody [N3C2], Internal detects TrxR1 protein at cytoplasm and nucleus in mouse liver by Immunohistochemical analysis. Sample: ...read more
Western Blot: thioredoxin reductase 1 Antibody [NBP2-20619] - Sample (30 ug of whole cell lysate)A: Molt-4 7. 5% SDS PAGE gel, diluted at 1:3000.
Western Blot: thioredoxin reductase 1 Antibody [NBP2-20619] - 50 ug mouse brain lysate/extract 7. 5% SDS-PAGE TrxR1 antibody [N3C2], Internal dilution: 1:1000.
Immunohistochemistry-Paraffin: thioredoxin reductase 1 Antibody [NBP2-20619] - Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-20619] - TrxR1 antibody [N3C2], Internal detects TrxR1 protein at cytoplasm and nucleus in mouse pancreas by immunohistochemical analysis. ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Pm, Po, Bv, Ca, Pm, Rb, RMSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Thioredoxin Reductase 1/TRXR1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human TrxR1. The exact sequence is proprietary.
Localization
Cytoplasm; Isoform 4: Cytoplasm; Nucleus; Isoform 5: Cytoplasm
Predicted Species
Porcine (93%), Bovine (93%), Rabbit (96%), Rhesus Macaque (98%), Canine (96%), Primate (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TXNRD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP2-20619 in the following applications:

  • IP
    1 publication
  • WB
    1 publication

Reactivity Notes

Monkey reactivity reported in scientific literature (Liang Z et al).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for Thioredoxin Reductase 1/TRXR1 Antibody

  • EC 1.8.1
  • EC 1.8.1.9
  • Gene associated with retinoic and IFN-induced mortality 12 protein
  • Gene associated with retinoic and interferon-induced mortality 12 protein
  • GRIM12
  • GRIM-12
  • GRIM-12TR1
  • KDRF
  • KM-102-derived reductase-like factor
  • MGC9145
  • oxidoreductase
  • Thioredoxin Reductase 1
  • thioredoxin reductase 1, cytoplasmic
  • thioredoxin reductase GRIM-12
  • Thioredoxin reductase TR1
  • TR
  • TR1
  • TRXR1
  • TRXRD1
  • TXNR
  • TXNRD1
  • TXNRTRXR1

Background

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-92630
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
AF5724
Species: Hu, Mu, Rt
Applications: ICC, WB
NBP2-52983
Species: Hu, Mu
Applications: Flow, ICC/IF, IHC, IHC-P, WB
NBP2-94256
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-26116
Species: Hu
Applications: IHC, IHC-P, PEP-ELISA, WB
NBP2-93808
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
DY417
Species: Mu
Applications: ELISA
NBP2-16684
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NB300-109
Species: Ch, Dr, Hu, I, Ma, Mu, Rt
Applications: Dual ISH-IHC, ICC/IF, IHC-FrFl, IHC-WhMt, IHC, IHC-Fr, IHC-P, KO, Simple Western, WB
NB100-58824
Species: Hu, Mu
Applications: ChIP, CHIP-SEQ, IP, WB
NBP1-89284
Species: Hu, Po
Applications: ICC/IF, IHC, IHC-P, KD, WB
H00055697-B01P
Species: Hu
Applications: ICC/IF, WB
NB100-2564
Species: Hu
Applications: WB
NBP2-01743
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, WB
NB200-322
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr, WB
NBP1-69023
Species: Mu
Applications: WB
NBP1-82756
Species: Hu
Applications: IHC, IHC-P
NBP2-20619
Species: Hu, Mu, Rt, Pm, Po, Bv, Ca, Pm, Rb, RM
Applications: WB, ICC/IF, IHC
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619)(1)

We have publications tested in 1 confirmed species: Monkey.

We have publications tested in 2 applications: IP, WB.


Filter By Application
IP
(1)
WB
(1)
All Applications
Filter By Species
Monkey
(1)
All Species
Showing Publication 1 - 1 of 1.
Publication using NBP2-20619 Applications Species
Liang Z, Zhu B, Meng D et al. Evaluation of the Effect of Carvedilol on the Thioredoxin Pathway in H9C2 Rat Cardiomyocytes Thesis (WB, IP, Monkey)

Details:
Green monkey
WB, IP Monkey

Reviews for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619) (0)

There are no reviews for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Thioredoxin Reductase 1/TRXR1 Products

Bioinformatics Tool for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619)

Discover related pathways, diseases and genes to Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619)

Discover more about diseases related to Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619).
 

Pathways for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619)

View related products by pathway.

PTMs for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619)

Learn more about PTMs related to Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619).
 

Research Areas for Thioredoxin Reductase 1/TRXR1 Antibody (NBP2-20619)

Find related products by research area.

Blogs on Thioredoxin Reductase 1/TRXR1

There are no specific blogs for Thioredoxin Reductase 1/TRXR1, but you can read our latest blog posts.
mFlour Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Thioredoxin Reductase 1/TRXR1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol TXNRD1
Uniprot