Thimet Oligopeptidase/THOP1 Antibody [DyLight 594]

• Reactivity: Hu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 594

Thimet Oligopeptidase/THOP1 Antibody [DyLight 594] Summary

• Immunogen: E. coli-derived recombinant human Oligopeptidase/THOP1
  Lys2-Cys689
  Accession # P52888
• Specificity: Detects human Oligopeptidase/THOP1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human Neurolysin is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: THOP1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Thimet Oligopeptidase/THOP1 Antibody [DyLight 594]

• EC 3.4.24
• EC 3.4.24.15
• Endopeptidase 24.15
• EP24.15
• MEPD_HUMAN
• MP78
• thimet oligopeptidase 1
• thimet oligopeptidase
• THOP1
• TOP

Background

Thimet oligopeptidase, a widely distributed enzyme in most species, plays a role in the metabolism of short neuropeptides (under 20 a.a. residues long). Thimet Oligopeptidase has an influential role in cytoplasmic peptide degradation. Other functions of Thimet Oligopeptidase include the degradation of amyloid precursor protein and the production of amyloidogenic fragments.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: THOP1