Thimet Oligopeptidase/THOP1 Antibody (455710) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 455710
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

Thimet Oligopeptidase/THOP1 Antibody (455710) [mFluor Violet 450 SE] Summary

• Immunogen: E. coli-derived recombinant human Thimet Oligopeptidase/THOP1
  Lys2-Cys689
  Accession # P52888
• Specificity: Detects human Thimet Oligopeptidase/THOP1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human Neurolysin is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: THOP1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Thimet Oligopeptidase/THOP1 Antibody (455710) [mFluor Violet 450 SE]

• EC 3.4.24
• EC 3.4.24.15
• Endopeptidase 24.15
• EP24.15
• MEPD_HUMAN
• MP78
• thimet oligopeptidase 1
• thimet oligopeptidase
• THOP1
• TOP

Background

Thimet oligopeptidase, a widely distributed enzyme in most species, plays a role in the metabolism of short neuropeptides (under 20 a.a. residues long). Thimet Oligopeptidase has an influential role in cytoplasmic peptide degradation. Other functions of Thimet Oligopeptidase include the degradation of amyloid precursor protein and the production of amyloidogenic fragments.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: THOP1