TGF-beta RII Antibody (RM0132-6G11)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
RM0132-6G11
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

TGF-beta RII Antibody (RM0132-6G11) Summary

Immunogen
Mouse recombinant protein of the extracellular domain of TGF beta RII
Specificity
This antibody detects mouse of TGF beta Receptor II in Western blotting. This antibody does not cross-react with mouse TGF beta Receptor I.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
TGFBR2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for TGF-beta RII Antibody (RM0132-6G11)

  • AAT3
  • EC 2.7.11
  • EC 2.7.11.30
  • FAA3
  • HNPCC6
  • LDS1B
  • LDS2B
  • MFS2
  • RIIC
  • TAAD2
  • tbetaR-II
  • TGF-beta receptor type II
  • TGF-beta receptor type IIB
  • TGF-beta receptor type-2
  • TGF-beta RII
  • TGF-beta type II receptor
  • TGFbetaRII
  • TGFbeta-RII
  • TGFBR2
  • TGF-bRII
  • TGFR-2
  • transforming growth factor beta receptor type IIC
  • transforming growth factor, beta receptor II (70/80kDa) isoform 1
  • transforming growth factor, beta receptor II (70/80kDa) isoform 2
  • transforming growth factor, beta receptor II (70/80kDa)
  • transforming growth factor, beta receptor II (70-80kD)
  • Transforming growth factor-beta receptor type II

Background

Transforming Growth Factor beta Receptor II (TGFBR2) belongs to the serine-threonine kinase family. It is involved in regulating cell proliferation and differentiation and extracellular matrix production and acts as a signal transducer. It phosphorylates TGFBR1 upon binding to its ligand, TGF-beta. TGFBR1 in turn phosphorylates the cytoplasmic effectors of the pathway, known as SMADs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TGFBR2
Entrez
Uniprot