TGF-beta RII Products

Antibodies
ELISA Kits
Human TGF-beta RII ELISA Kit ...
Human TGF-beta RII ELISA Kit (Colo...
NBP2-60148
Species: Hu
Applications: ELISA
Lysates
TGF-beta RII Overexpression L ...
TGF-beta RII Overexpression Lysate...
NBL1-16857
Applications: WB
Proteins
Recombinant Human TGF-beta RI ...
Recombinant Human TGF-beta RII Pro...
NBP2-50573
Species: Hu
Applications: PAGE
RNAi
TGF-beta RII RNAi
TGF-beta RII RNAi
H00007048-R08
Species: Hu
Applications: RNAi, RNAi SP
TGF-beta RII RNAi
TGF-beta RII RNAi
H00007048-R07
Species: Hu
Applications: RNAi, RNAi SP

Description

TGF beta Receptor II is a total of three members of the TGFbeta family, TGFbeta1, TGFbeta2 and TGFbeta3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFbetas mediate their activity by high affinity binding to the type II receptor (TGFbeta RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses the type II receptor requires both its kinase activity and association with a TGFbeta-binding protein, designated the type I receptor. Two independent groups have recently described the cloning and sequence analysis of genes encoding TGFbeta type I receptor proteins designated ALK-5 (TbetaR-1) and TSR-1, respectively.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 7048
Alternate Names
  • EC 2.7.11
  • FAA3
  • HNPCC6
  • transforming growth factor, beta receptor II (70-80kD)
  • TbetaR-II
  • MFS2
  • transforming growth factor, beta receptor II (70/80kDa) isoform 2
  • LDS2B
  • transforming growth factor, beta receptor II (70/80kDa) isoform 1
  • LDS1B
  • transforming growth factor beta receptor type IIC
  • AAT3
  • TGF-beta receptor type-2
  • EC 2.7.11.30
  • TGF-beta receptor type IIB
  • TGF-beta type II receptor
  • tbetaR-II
  • TGF-beta receptor type II
  • TGFbeta-RII
  • TGFR-2
  • TAAD2
  • Transforming growth factor-beta receptor type II
  • RIIC
  • transforming growth factor, beta receptor II (70/80kDa)

Research Areas for TGF-beta RII

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cell Cycle and Replication

PTMs for TGF-beta RII

Learn more about PTMs related to TGF-beta RII.

Phosphorylation
Methylation
Acetylation
Ubiquitination
Reduction
Deacetylation
Glycosylation

Bioinformatics Tool for TGF-beta RII

Discover related pathways, diseases and genes to TGF-beta RII. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.