Tenascin C Antibody (4C8MS) [DyLight 488]

Images

 
There are currently no images for Tenascin C Antibody (NB110-68136G).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P
Clone
4C8MS
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Tenascin C Antibody (4C8MS) [DyLight 488] Summary

Immunogen
Recombinant human Tenascin C [Swiss-Prot# P24821].
Localization
Secreted > extracellular space > extracellular matrix
Specificity
NB110-68136 specifically reacts with Domain B on FNIII repeats of Tenascin C.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNC
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
This Tenascin C (4C8MS) antibody is useful for Immunohistochemistry on paraffin-embedded sections, Immunocytochemistry/Immunofluorescence (PMID: 21871891) and Western blot. Immunohistochemistry-Frozen and ELISA were reported in scientific literature.

Reactivity Notes

Human, mouse and rat.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Tenascin C Antibody (4C8MS) [DyLight 488]

  • 150-225
  • Cytotactin
  • Glioma-associated-extracellular matrix antigen
  • GMEM
  • GP 150-225
  • hexabrachion (tenascin C, cytotactin)
  • hexabrachion (tenascin)
  • Hexabrachion
  • HXB
  • HXBcytotactin
  • JI
  • MGC167029
  • Myotendinous antigen
  • neuronectin
  • Tenascin C
  • Tenascin J1
  • tenascin
  • tenascin-C isoform 14/AD1/16
  • Tenascin-C
  • TNC
  • TN-C
  • TNGP

Background

In most tissues of adults, tenascin C is rarely present at significant levels. However, in developing tissues, or tissues experiencing a fast rate of growth, tenascin C is upregulated. This effect is particularly evident when this extracellular matrix glycoprotein is found in abundance in tissues responding to injury or infection. When muscular pH is increased, tenascin C production also increases. Prostate smooth muscle cells produce extra tenascin C when responding to LPS infection. In fibrosis and stenosis, tenascin C expression levels are markedly increased, and the protein seems to function as a mobilizer of immune cells responding to tissue damage and repair. In COPD, likewise, tenascin C expression is increased and is associated with cells attempting to repair damage within the lung. In short, tenascin C can be expected to be found in adult tissues only when associated with tissue damage and repair efforts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-91258
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP1-39497
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, RIA
NBP2-37384
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-P
AF3865
Species: Hu
Applications: WB, IHC
NBP2-45397
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-28872
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP1-87822
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-88899
Species: Hu
Applications: IHC, IHC-P
AF6999
Species: Hu
Applications: WB, Simple Western, IHC
NB600-1342
Species: Hu, Mu, Rt, Bv
Applications: WB, Func, IA, IHC, IHC-Fr, IHC-P, IP
NBP1-76941
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP1-84550
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-24916
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
NB100-524
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP, Flow-IC
AF1095
Species: Hu
Applications: WB, Simple Western, IHC, CyTOF-ready, ICC, ICFlow
NB110-68136G
Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P

Publications for Tenascin C Antibody (NB110-68136G) (0)

There are no publications for Tenascin C Antibody (NB110-68136G).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Tenascin C Antibody (NB110-68136G) (0)

There are no reviews for Tenascin C Antibody (NB110-68136G). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Tenascin C Antibody (NB110-68136G). (Showing 1 - 1 of 1 FAQ).

  1. One of our clients is looking for antibodies against tenascin C and fibronectin that could be used for FFPE rat tissues. These antibodies should exclusively recognize tenascin C and fibronectin and do not cross react with each other. Can you inform me if you have these antibodies?
    • Here is a link to Tenascin C antibodies we have validated in rat tissues for IHC-P Here are antibodies we have validated in fibronectin in rat tissues for IHC-P

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB110-68136APC
Biotin Labeled NB110-68136B
DyLight 350 Labeled NB110-68136UV
DyLight 405 Labeled NB110-68136V
DyLight 550 Labeled NB110-68136R
DyLight 650 Labeled NB110-68136C
DyLight 680 Labeled NB110-68136FR
DyLight 755 Labeled NB110-68136IR
FITC Labeled NB110-68136F
HRP Labeled NB110-68136H
PE Labeled NB110-68136PE

Additional Tenascin C Products

Related Products by Gene

Bioinformatics Tool for Tenascin C Antibody (NB110-68136G)

Discover related pathways, diseases and genes to Tenascin C Antibody (NB110-68136G). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Tenascin C Antibody (NB110-68136G)

Discover more about diseases related to Tenascin C Antibody (NB110-68136G).
 

Pathways for Tenascin C Antibody (NB110-68136G)

View related products by pathway.

PTMs for Tenascin C Antibody (NB110-68136G)

Learn more about PTMs related to Tenascin C Antibody (NB110-68136G).
 

Research Areas for Tenascin C Antibody (NB110-68136G)

Find related products by research area.

Blogs on Tenascin C

There are no specific blogs for Tenascin C, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Tenascin C Antibody (4C8MS) [DyLight 488] and receive a gift card or discount.

Bioinformatics

Gene Symbol TNC
Entrez
Uniprot

Customers Who Bought This Also Bought

Tenascin C RNAi
H00003371-R01-20nmol