Tenascin C Products

Antibodies
Tenascin C Antibody (578) [Un ...
Tenascin C Antibody (578) [Unconju...
MAB2138
Species: Hu, Mu
Applications: WB, B/N, ICC/IF
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
Tenascin C Antibody [Unconjug ...
Tenascin C Antibody [Unconjugated]
AF3358
Species: Hu
Applications: WB, ICC/IF
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
ELISA Kits
Rat Tenascin C ELISA Kit (Col ...
Rat Tenascin C ELISA Kit (Colorime...
NBP2-78768
Species: Rt
Applications: ELISA
Human Tenascin C ELISA Kit (C ...
Human Tenascin C ELISA Kit (Colori...
NBP2-78766
Species: Hu
Applications: ELISA
Mouse Tenascin C ELISA Kit (C ...
Mouse Tenascin C ELISA Kit (Colori...
NBP2-78767
Species: Mu
Applications: ELISA
Lysates
Tenascin C Knockout HeLa Cell ...
Tenascin C Knockout HeLa Cell Lysate
NBP2-77129
Species: Hu
Applications: WB
Proteins
Recombinant Human Tenascin C ...
Recombinant Human Tenascin C Prote...
3358-TC
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Tenascin C Recombinant Protei ...
Tenascin C Recombinant Protein Ant...
NBP1-89639PEP
Species: Hu
Applications: AC

Description

Tenascin, also known as hexabrachion and cytotactin, is an extracellular matrix protein with a spatially and temporally restricted tissue distribution. It is a hexameric, multidomain protein with disulfide linked subunits of 190 to 240 kD, originally characterized as 'myotendinous antigen.' In the embryo it is present in dense mesenchyme surrounding developing epithelia and in developing cartilage and bone. In the adult, tenascin remains present in tendons and myotendinous junctions in the perichondrium and periosteum, as well as in smooth muscle. Tenascin (TN)(Erickson and Bourdon 1989, Erickson 1993) is a high molecular weight, multifunctional, extracellular matrix glycoprotein, expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors. It has been described under a variety of names: cytotactin, hexabrachion protein, J1-200/220, myotendinous antigen (MI), neuronectin (NEC1) and glioma mesenchymal extracellular matrix (GMEM). The TN molecule is a disulfide-linked hexamer. Human TN has 3 subunits of 190, 200 and 220 kDa. It is primarily made up of 14.5 epidermal growth-factor-like repeats, 15 units similar to the fibronectin type-III-homology repeat and, at the C-terminus, has a sequence with homology to the globular domain of the beta and gamma chain of fibrinogen. Monoclonal antibody reacting specifically with tenascin is an essential tool for the localization, identification and studies on the role of the molecule in epithelial-mesenchymal and neuronal-glial interactions (Castellucci et al. 1991, Balza et al. 1993).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 3371
Alternate Names
  • Tenascin-C
  • hexabrachion (tenascin C, cytotactin)
  • Neuronectin
  • GP 150-225
  • Hexabrachion
  • TN-C
  • Cytotactin
  • JI
  • tenascin-C isoform 14/AD1/16
  • GMEM
  • tenascin
  • Myotendinous antigen
  • neuronectin
  • Glioma-associated-extracellular matrix antigen
  • hexabrachion (tenascin)
  • MGC167029
  • HXBcytotactin
  • TNGP
  • 150-225
  • tenascin C

Research Areas for Tenascin C

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Extracellular Matrix
Neuroscience
Prostate Cancer

Bioinformatics Tool for Tenascin C

Discover related pathways, diseases and genes to Tenascin C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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