TBX20 Antibody (668710) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 668710
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

TBX20 Antibody (668710) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human TBX20
  Met1-Leu116
  Accession # Q9UMR3
• Specificity: Detects human TBX20 in ELISA.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TBX20 Antibody (668710) [Alexa Fluor® 532]

• ASD4
• T-box 20
• T-box protein 20
• T-box transcription factor TBX20
• TBX20

Background

TBX20 (T-box transcription factor 20) is a transcriptional activator and repressor that is essential for cardiac development and to adult cardiomyocyte function. Mutation in humans or mice can result in congenital heart disease, including septation, chamber, and valvulogenesis defects and dilated cardiomyopathy. These include atrial septal defect 4 (ASD4). The 447 amino acid (aa) human TBX20 contains a T-box DNA binding domain at aa 109-228. Between aa 1-116, human TBX20 shares 96% aa sequence identity with mouse TBX20. One isoform that is truncated at aa 297 has been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.