TARBP1 Antibody - BSA Free

Western Blot: TARBP1 Antibody [NBP1-76400] - 3T3 cell lysate with TRBP1 antibody at (A) 1 and (B) 2 ug/mL.

• Reactivity: Hu, Mu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TARBP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit TARBP1 Antibody - BSA Free (NBP1-76400) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1. The immunogen is located within amino acids 1310 - 1360 of TRBP1. Amino Acid Squence: HGAGNAKKNWQRIQEHF
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TARBP1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1-2 ug/ml
• Theoretical MW: 182 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  TARBP1 Peptide (NBP1-76400PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for TARBP1 Antibody - BSA Free

• EC 2.1.1.-
• FLJ30482
• TAR (HIV-1) RNA binding protein 1
• TAR RNA loop binding protein
• TAR RNA-binding protein 1
• TAR RNA-binding protein of 185 kDa
• tardbp1
• TRM3probable methyltransferase TARBP1
• TRP-185TAR (HIV) RNA binding protein 1
• TRP185TAR (HIV) RNA-binding protein 1

Background

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TARBP1
• Entrez:
  • 6894(Human)
• Uniprot:
  • Q13395(Human)