TAB2 Antibody (3B5)

Images

 
Western Blot: TAB2 Antibody (3B5) [NBP1-51668] - Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2-hIgGFc transfected HEK293 (2) cell lysate.
Flow Cytometry: TAB2 Antibody (3B5) [NBP1-51668] - Flow cytometric analysis of HL-60 cells using TAB2 mouse mAb (green) and negative control (purple).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow
Clone
3B5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

TAB2 Antibody (3B5) Summary

Immunogen
Purified recombinant fragment of human TAB2 expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TAB2
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
  • Flow Cytometry 1:200-1:400
Application Notes
This antibody is useful in Western Blot, ELISA, Flow Cytometry. Although not tested this anitbody may be useful in Immunofluorescence/Immunocytochemistry.
Theoretical MW
80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for TAB2 Antibody (3B5)

  • FLJ21885
  • KIAA0733CHTD2
  • MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2
  • Mitogen-activated protein kinase kinase kinase 7-interacting protein 2
  • TAB-2
  • TAK1-binding protein 2
  • TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
  • TGF-beta-activated kinase 1-binding protein 2

Background

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TAB2