Synaptopodin Antibody Blocking Peptide Summary
| Description |
A blocking peptide containing 17 amino acids near the carboxy terminus of human SYNPO. Source: Synthetic (Accession #: NP_001159680) |
| Source |
Synthetic |
| Protein/Peptide Type |
Antibody Blocking Peptide |
| Gene |
SYNPO |
| Purity |
N/A |
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This peptide is useful as a blocking peptide for NBP2-39100. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin. |
| Preservative |
0.02% Sodium Azide |
| Concentration |
0.2 mg/ml |
| Purity |
N/A |
Alternate Names for Synaptopodin Antibody Blocking Peptide
Background
SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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