Stonin-1 Antibody - BSA Free

Western Blot: Stonin-1 Antibody [NBP1-80795] - Analysis in human cell line NTERA-2.

Immunohistochemistry-Paraffin: Stonin-1 Antibody [NBP1-80795] - Staining of human fallopian tube shows strong cytoplasmic positivity in glandular cells.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Stonin-1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Stonin-1 Antibody - BSA Free (NBP1-80795) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. Anti-Stonin-1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: DSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDCAFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAENQDSLR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STON1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  SALF Recombinant Protein Antigen (NBP1-80795PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Stonin-1 Antibody - BSA Free

• DKFZp781K2462
• FLJ95267
• MGC149803
• MGC149804
• SALF
• SBLFstoned-b1
• STN1
• STNB1
• stoned B homolog 1
• Stoned B-like factor
• stonin 1
• stonin-1

Background

Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Co-transcription of this gene and the neighboring downstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Stonin-1 Antibody (NBP1-80795)(2)

Publications using NBP1-80795

• Milstead RA, Link CD, Xu Z, Hoeffer CA TDP-43 knockdown in mouse model of ALS leads to dsRNA deposition, gliosis, and neurodegeneration in the spinal cord Cerebral cortex (New York, N.Y. : 1991) 2022-11-28 [PMID: 36443249]
• Legartova S, Svobodova Kovarikova A, Behalova Suchankova J et al. Early recruitment of PARP-dependent m8A RNA methylation at DNA lesions is subsequently accompanied by active DNA demethylation RNA biology 2022-01-01 [PMID: 36382943] (ICC/IF, Human)

Bioinformatics

• Gene Symbol: STON1
• Entrez:
  • 11037(Human)
• Uniprot:
  • Q9Y6Q2(Human)