Steroid sulfatase Antibody - BSA Free

Analysis in human placenta and pancreas tissues using Anti-STS antibody. Corresponding STS RNA-seq data are presented for the same tissues.

Product Discontinued

Steroid sulfatase Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: YEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIY
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STS
• Purity: Affinity purified

Applications/Dilutions

• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Steroid sulfatase Protein (NBP1-90095PEP)

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 25817828).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Steroid sulfatase Antibody - BSA Free

• ARSC1
• ARSC1ES
• ARSCsteroid sulfatase (microsomal), arylsulfatase C, isozyme S
• Arylsulfatase C
• ASC
• EC 3.1.6
• EC 3.1.6.2
• Estrone sulfatase
• SSDD
• steroid sulfatase (microsomal), isozyme S
• Steroid sulfatase
• steryl-sulfatase
• Steryl-sulfate sulfohydrolase
• STS
• XLI

Background

Steroid sulfatase is encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Steroid sulfatase Antibody (NBP1-90095)(3)

Publications using NBP1-90095

• Ren X, Wu X, Hillier SG et al. Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy. J Steroid Biochem Mol Biol 2015-06-01 [PMID: 25817828] (IF/IHC, Human)
• Drukker M, Tang C, Ardehali R et al. Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol 2012-05-01 [PMID: 22634564]
• Colette S, Defrere S, Lousse JC et al. Inhibition of steroid sulfatase decreases endometriosis in an in vivo murine model. Hum Reprod 2011-06-01 [PMID: 21441545]

Bioinformatics

• Gene Symbol: STS