Stabilin-1 Antibody

Immunohistochemistry-Paraffin: Stabilin-1 Antibody [NBP1-52152] - Staining of Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu, Po, Bv, Ca
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Stabilin-1 Antibody Summary

• Immunogen: Peptide with sequence C-DFPDTQRILTVK corresponding to C-Terminus according to NP_055951.2.
• Epitope: C-DFPDTQRILTVK
• Predicted Species: Porcine (100%), Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: STAB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 3 - 5 ug/ml
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Peptide ELISA Detection limit 1:8000
• Application Notes: IHC-P: Human spleen shows endothelial staining.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Stabilin-1 Antibody

• CLEVER-1
• fasciclin egf-like, laminin-type egf-like, and link domain-containing scavengerreceptor-1
• Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavengerreceptor 1
• FEEL1
• FEEL-1
• FEEL-1MS-1 antigen
• FELE-1
• FEX1
• KIAA0246common lymphatic endothelial and vascular endothelial receptor-1
• MS-1 Antigen
• STAB1
• STAB-1
• stabilin 1
• Stabilin1
• Stabilin-1

Background

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Stabilin-1 Antibody (NBP1-52152)(1)

Publication using NBP1-52152

• Salmi M, Koskinen K, Henttinen T et al. CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium. Blood 2004-12-01 [PMID: 15297319]

Bioinformatics

• Gene Symbol: STAB1
• Entrez:
  • 23166(Human)
• Uniprot:
  • NP_055951.2(Human)