Stabilin-1 Products

Description

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq]

Bioinformatics

Entrez	23166 Human
Uniprot	NP_055951 Human
Product By Gene ID	23166
Alternate Names	CLEVER-1 fasciclin egf-like, laminin-type egf-like, and link domain-containing scavengerreceptor-1 Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavengerreceptor 1 FEEL1 FEEL-1 FEEL-1MS-1 antigen FELE-1 FEX1 KIAA0246common lymphatic endothelial and vascular endothelial receptor-1 MS-1 Antigen STAB1 STAB-1 stabilin 1 Stabilin1 Stabilin-1