ST6GALNAC1 Antibody

Western Blot: ST6GALNAC1 Antibody [NBP2-20493] - Sample (30 ug of whole cell lysate) A: HeLa 10% SDS PAGE diluted at 1:1000

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

ST6GALNAC1 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human ST6GALNAC1. The exact sequence is proprietary.
• Localization: Golgi apparatus membrane; Single-pass type II membrane protein
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ST6GALNAC1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 69 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for ST6GALNAC1 Antibody

• alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
• EC 2.4.99.3
• GalNAc alpha-2, 6-sialyltransferase I, long form
• GalNAc alpha-2,6-sialyltransferase I
• sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase) A
• Sialyltransferase 7A
• Siat7A
• SIAT7-A
• ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 1
• ST6GalNAc I
• ST6GALNAC1
• ST6GalNAcI
• ST6GalNAcIHSY11339
• STYI

Background

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: ST6GALNAC1
• Uniprot:
  • Q9NSC7()