ST6GALNAC1 Antibody - BSA Free

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Analysis in human rectum and skeletal muscle tissues. Corresponding ST6GALNAC1 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Staining of human stomach shows strong positivity in Golgi apparatus in glandular cells.

• Reactivity: Hu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ST6GALNAC1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ST6GALNAC1 Antibody - BSA Free (NBP1-87043) is a polyclonal antibody validated for use in IHC and ICC/IF. Anti-ST6GALNAC1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: PQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGN
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ST6GALNAC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence Reported in scientific literature (PMID: 30401951)
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  ST6GALNAC1 Protein (NBP1-87043PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ST6GALNAC1 Antibody - BSA Free

• alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
• EC 2.4.99.3
• GalNAc alpha-2, 6-sialyltransferase I, long form
• GalNAc alpha-2,6-sialyltransferase I
• sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase) A
• Sialyltransferase 7A
• Siat7A
• SIAT7-A
• ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 1
• ST6GalNAc I
• ST6GALNAC1
• ST6GalNAcI
• ST6GalNAcIHSY11339
• STYI

Background

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ST6GALNAC1 Antibody (NBP1-87043)(2)

Publications using NBP1-87043

• Mayr J, Lau K, Lai JCC et al. Unravelling the Role of O-glycans in Influenza A Virus Infection. Sci Rep. 2018-11-06 [PMID: 30401951] (ICC/IF, Human)
• Jia N, Barclay WS, Roberts K et al. Glycomic characterisation of respiratory tract tissues of ferrets: implications for its use in influenza virus infection studies. J Biol Chem. 2014-08-18 [PMID: 25135641] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: ST6GALNAC1