ST3GAL6 Antibody - BSA Free

Western Blot: ST3GAL6 Antibody [NBP1-77353] - HeLa cell lysate with ST3gal6 antibody at (A) 1 and (B) 2 ug/mL.

Immunocytochemistry/ Immunofluorescence: ST3GAL6 Antibody - BSA Free [NBP1-77353] - Immunocytochemistry of ST3GAL6 in HeLa cells with ST3GAL6 antibody at 5 ug/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

ST3GAL6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ST3GAL6 Antibody - BSA Free (NBP1-77353) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ST3gal6. The immunogen is located within amino acids 230 - 280 of ST3gal6. Amino Acid Squence: PKVFPKNQKPKHPTTG
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ST3GAL6
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  ST3GAL6 Peptide (NBP1-77353PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for ST3GAL6 Antibody - BSA Free

• alpha2,3-sialyltransferase
• CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI
• EC 2.4.99
• EC 2.4.99.-
• EC 2.4.99.9
• Sialyltransferase 10
• SIAT10
• ST3 beta-galactoside alpha-2,3-sialyltransferase 6
• ST3Gal VI
• ST3GAL6
• ST3GALVI
• ST3GALVIsialyltransferase 10 (alpha-2,3-sialyltransferase VI)
• type 2 lactosamine alpha-2,3-sialyltransferase

Background

Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ST3GAL6
• Uniprot:
  • NP_006091()